MAPK8 and Allergy: Similarly, Wang et al. recently proposed that inflammation signaling induced by ovalbumin-affected allergy could be involved in increased TLR4 and subsequent activation of phospholate-Jun-N-terminal kinase (p-JNK), JNK1/2 (p-NFkB), p-IkB and TNF-α in the hearts of allergy-prone mice [56].