INS and Insulin resistance: Meta-analysis of 21 GWAS cohorts (Meta-Analyses of Glucose and Insulin-related traits Consortium [MAGIC]), identified associations between a number of SNPs in 8 loci (including the candidate genes ADCY5, FADS1, and GLIS3) and fasting glucose concentrations, and also between SNPs in one locus (with the candidate gene IGF1) with both fasting insulin levels and insulin resistance [71].