Germ-line mutations of the STK11 gene are associated with Peutz-Jeghers syndrome (PJ)[11,12], an autosomal dominant disorder characterized by hamartomatous polyps of the gastrointestinal tract and by a considerably increased risk of cancer in gastrointestinal tract, pancreas, breast, lung, uterus, cervix, ovary and testis[16-18]. The gene discussed is STK11; the disease is cancer.