With respect to grave vascular hypertensive changes, glomerular sclerosis in association with extensive tubulointerstitial scarring (65%), deposits IgA in the mesangium, and typical figures characteristic of FD as were mentioned, it is not possibly to clearly say what was the main cause of the end stage renal disease in this young 26 year-old man. The gene discussed is CD79A; the disease is Glomerular sclerosis.