In cases of BA, biochemical liver function tests are typically those of cholestasis, with elevated levels of total and conjugated bilirubin (>20 umol/L total bilirubin, of which >20% is conjugated), increased gamma-glutamyl transpeptidase and alkaline phosphatase, and sometimes slightly higher than normal transaminases [43]. The gene discussed is GGTLC1; the disease is breast angiosarcoma.