SCN5A and sudden infant death syndrome: In 2000 and 2001, a number of case reports were published on mutations in LQTS genes in SIDS or near SIDS [179–181], starting with the description by Schwartz et al. [179] of an infant who nearly died of SIDS and in whom LQTS was diagnosed and a spontaneous mutation in SCN5A was identified, providing a “proof of concept” of cardiac ion channelopathies as a cause of SIDS.