Many other genes have been suggested to be useful as a potential marker for stratifying low-risk PCa patients, like engrailed-2 (EN2) [51], caveolin-1 (CAV-1) [52], secreted protein acidic and rich in cysteine-like 1 (SPARCL1) [53], and breast cancer anti-estrogen resistance protein 1 (BCAR1) [54]. The gene discussed is EN2; the disease is posterior cortical atrophy.