Cell markers such as PARP and caspase-3 were not cleaved to active forms in AE-SN treated-endometrial adenocarcinoma cells, suggesting that the tested HEC1A, HEC1B, and KLE cells were capable of evading the apoptotic pathways activated by AE-SN, but were still vulnerable to AE-SN-induced autophagic cell death. This evidence concerns the gene CASP3 and endometrium adenocarcinoma.