Therefore, MART-10 possesses the combined characteristics of the noncalcemic nature of the 19-nor vitamin D compounds [30] as exemplified by the FDA-approved drug Zemplar or 19-nor-1α, 25(OH)2D2 for the treatment of the secondary hyperparathyroidism, and the enhanced VDR binding property of 2α-(3-hydroxy)propyl compound [31, 32]. This evidence concerns the gene VDR and secondary hyperparathyroidism.