On November 2010, two and a half months after the onset of the gouty attack, the patient still persisted with significant polyarthritis associated to elevated erythrocyte sedimentation rate (ESR) of 75 mm and C-reactive protein (CRP) of 278 mg/dL, even in the presence of low serum levels of uric acid (Figure 1). This evidence concerns the gene CRP and polyarticular arthritis.