FAF1 mRNA expression level was lower in stage IV gastric cancer tissue (0.18 ± 0.12) than in Stage I + II (0.32 ± 0.12) or stage IIIA + IIIB cancer tissue (0.30 ± 0.11, F = 6.276, P = 0.004), and it was lower in gastric cancer with distant metastasis than in gastric cancer without distant metastasis (0.19 ± 0.07 versus 0.29 ± 0.12, t = −2.753, P < 0.01). Here, FAF1 is linked to gastric cancer.