LMO1 and acute lymphoblastic leukemia: We next undertook chromatin immunoprecipitation assays in nuclei generated from Jurkat, a nontranslocated LMO1-expressing T-ALL cell line as well as a nontranslocated LMO1 expressing T-ALL patient sample using an antibody to acetylated histone H3, as this histone modification marks active promoters and enhancers (Figure 4c).