The CD44+/CD24−/low/ESA+ BCSC subpopulation from MDA-MB-231 and BCM2 cells also expressed the EMT markers such as vimentin and snail and decreased expression of E-cadherin and displayed higher mammosphere-forming capacity, tumourigenicity and metastatic potential to lungs as compared with parental breast cancer cell lines [79]. This evidence concerns the gene CD44 and breast carcinoma.