Given that the migration of DCs infected with O. tsutsugamushi was considerably impaired, preferential secretion of the CC chemokine subfamily, which includes RANTES and MIP-1α from O. tsutsugamushi-infected DCs at the infection site may contribute to the infiltration of monocytes and lymphocytes into the infection sites as observed in the eschars from scrub typhus patients [9]. Here, CCL5 is linked to infection.