In addition, in previous papers, we have reported that the adhesion of C. albicans to hepatic sinusoidal endothelial (HSE) cells triggers a pro-inflammatory cytokine-mediated immune response, which contributes to the adhesion of B16 melanoma (B16M) cells and metastasis [12] by increasing the expression of the vascular cell adhesion molecule-1 (VCAM-1) [13]. This evidence concerns the gene VCAM1 and melanoma.