Similar to the results in Fig. 5C and 5D, the quantification of both blood vessels and tumor weight showed that inhibition of AKT activity suppressed the promoting effect of Tat on vIL-6-induced angiogenesis and tumorigenesis of endothelial cells in the CAM model (Fig. 5G, 5H, 5I, 5J). This evidence concerns the gene TAT and neoplasm.