The theoretical daily burden of CML ingested from formulas, calculated on the basis of determined CML content of formula [14] and daily dosage specified by the manufacturers, ranged from 8.8 mg/day to 10.3 mg/day in infants consuming high-CML-containing formulas, while those on low-CML-containing formulas ingested amounts from 1.8 mg/day to 2.2 mg/day. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.