Having obtained promising results, our approach has been proven to be effective due to (A) multiple datasets from age and sex-matched, large size of schizophrenia and healthy control samples filtered for homogenous European ethnicities; (B) dense and quality SNP markers of ERBB4/NRG1 with an average 99% for genotyping call rate for SNPs and individuals. Here, ERBB4 is linked to schizophrenia.