AIF1 and Stroke: Both gene transcripts, Iba1 and CD68, were reduced in TREM2-KO mice at day 7 after stroke (KO vs. WT; Iba1∶46% ±3.7, CD68∶20% ±2.0, p≤0.05, n = 5/6 each; Figure 2C), while no significant differences were observed at 12 h and 28 d after stroke (Figure 2C).