EZH2 and neoplasm: We did not observe significant association between EZH2 expression in tumor or adjacent normal lung and clinicopathological parameters, beside a statistically insignificant association of smoking and EZH2 expression in the tumor (P = 0.1), and a borderline correlation between clinical stage and EZH2 expression in tumor compared to adjacent normal lung tissues (P = 0.07, Table 1).