IFNG and familial dilated cardiomyopathy: As illustrated in Fig. 7A, the addition of IgG isolated from β1-AA-positive sera of DCM patients caused a reduction in IFN-γ production (6.788±1.46 pg/ml vs. vehicle group 56.22±2.29 pg/ml, p<0.01; 6.788±1.46 pg/ml vs. Negative IgG group 22.96±0.905 pg/ml, p<0.01) (Fig. 7A).