PAGR1 and Bernard-Soulier syndrome: As expected, there was severe attenuation of platelet aggregation with RIST in the BSS patients compared to normal blood (Figure 7E,J,O; Table 4), but other platelet activators tested (AA, COL, PA-1, and PA-4; example provided for PA-1 in Figure D, I, N) appeared quantitatively similar to the blood of normal controls (Table 4).