Recently, Tanji et al. revealed that Atg-8 homologues, LC3 and γ-aminobutyric-acid type A receptor associated proteins (GABARAPs), were localized in Lewy bodies in PD and DLB, suggesting that autophagic function is impaired through alteration of Atg8 homologues in Lewy body disease [33]. The gene discussed is MAP1LC3A; the disease is Parkinson disease.