CD14 and disease arising from reactivation of latent virus: Although we did not detect lytic viral transcripts (Fig. 4C), an increase in viral copy number (Fig. 5B), or the production of infectious virus (Fig. 6) by 20 dpi in FIX-ΔLUNA infected CD14+ cells, the low levels of UL138 may indicate that FIX-ΔLUNA did not fully establish a latent infection, but possibly a non-productive persistent infection.