In previous reports we analyzed the expression of several MMPs and TIMPs (MMP-1, 2, 7, 9, 11, 13 and 14, and TIMP-1, 2 and 3), either at the invasive front or at the tumor center of breast carcinomas, in many of the women included in the present study [25]–[28]. The gene discussed is MMP1; the disease is breast carcinoma.