Next, we performed a multivariate survival analysis based on the Cox proportional hazard model for all parameters found to be significant by univariate analyses, including stromal CD271 expression, pT category, lymph node metastasis, UICC stage, perilymphatic invasion, perivascular invasion, and pathologic margin positivity (Table S2). The gene discussed is NGFR; the disease is metastatic malignant neoplasm in the lymph nodes.