PTH and osteoporosis: In combination, our current findings, numerous previous reports on the importance of PTH signaling on bone homeostasis and the fact that free circulating LCPUFA are present in blood at concentrations used in this study clearly calls for more detailed studies of the role of LCPUFA on PTH pathway both in in-vitro and in-vivo models as it may contribute to development of alternative approaches for treatments of bone diseases such a osteoporosis.