The C allele of the SNP rs2721173, located in the gene region RecQ protein-like 4 (RECQL4), was associated with an increased risk of melanoma (OR = 1.35, 95% CI: 1.13, 1.62; P-trend = 1.13×10−3; Figures S1 and S2 and Tables S2 and S3). Here, RECQL4 is linked to melanoma.