Furthermore, T cells exposed to tol-DCs from Crohn’s disease patients exhibited a significantly reduced capacity to proliferate (mean cpm = 20561±13058 vs 38181±18177; p = 0.037) compared to mDCs, as well as reduced IFN-γ secretion when co-cultured with fully competent mDCs (figure 8C). Here, IFNG is linked to Crohn disease.