MBP and myeloid sarcoma: Other MBP EAE passive models in rats used MOG antibody injections in order to study the role of autoantibodies in the pathogenesis of MS [23], [24], but in these models the antibody is injected and there are few B cells present in the CNS making difficult the study of any direct role of B cells in the pathogenesis that is not mediated by antibodies.