INS and coronary artery disorder: In a random-effect meta-analysis the pooled relative risk of CHD comparing the highest versus the lowest category was 1.52 (95% CI: 1.31, 1.76; I2∶62.4%) for glucose, 1.12 (95% CI: 0.92, 1.37; I2∶41.0%) for insulin and 1.64 (95% CI: 1.35, 2.00; I2∶0%) for HOMA-IR (Figure 2 and Figure S1).