APOL1 and glomerulosclerosis: Reports of the correlation between APOL1 and glomerulosclerosis prompted the development of genetic tests for the G1 and G2 alleles [12], the proposal of “APOL1 glomerulosclerosis” as a distinct disease entity [16], and the suggestion that selected African-Americans might benefit from screening for G1 and G2 alleles including potential kidney donors and asymptomatic HIV+ patients as an indication for early initiation of HAART [17].