MYH9 and glomerular disorder: As described in the Introduction, the initial assumption that MYH9 was the causal disease gene was based on both the high genome wide correlation of polymorphisms, and because rare, autosomal dominant MYH9 mutations in patients with Epstein's and Fetchner's syndrome result in a glomerular disease that is histologically similar to idiopathic FSGS [2], [3], [46].