HTT and neoplasm: Microarray data revealed that mesenchymal-associated genes and genes encoding extracellular matrix ECM remodelling proteins associated with EMT were up-regulated in the polyQ-huntingtin-expressing tumours as compared to control tumours, including the genes MMP2 (FC = 1.66; p-value = 3.92 × 10−3) and MMP3 (FC = 2.47; p-value = 1.58 × 10−2; Supporting Information Table S1).