NFKB1 and bacterial vaginosis: Interestingly, a non-vaginal lactobacillus species (L. kefiranofaciens) induced production of MIP-3α [55] and other vaginal bacteria, associated with bacterial vaginosis e.g. P. bivia and A. vaginae induced simultaneous NF-κB activation and upregulation of inflammatory proteins in contrast to vaginal L. crispatus and L. acidophilus, which maintained low levels of proinflammatory proteins in the vaginal colonization context [20].