Of eight randomly selected HLA-A2 positive patients, CD8+ T-cells were isolated at baseline and on day 8 after Selectikine infusion during the second cycle, and stimulated with a panel of peptides representing cancer-testis antigenic epitopes from the tumor antigens Melan-A, MAGE-A3, MAGE-A10, NY-ESO-1 and SSX-2. The gene discussed is CD8A; the disease is neoplasm.