Furthermore, knockdown of abnormal spindle microcephaly (ASPM), a causative gene for autosomal recessive primary microcephaly (MCPH, for microcephaly primary hereditary), disturbs neuronal migration as well as neural progenitor proliferation in mice (Fish et al. 2006; Buchman et al. 2011). Here, ASPM is linked to autosomal recessive primary microcephaly.