CD209 and dengue disease: The Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin (DC-SIGN, also called CLEC4L and CD209) proteins have been extensively studied, due to their broad range recognition of pathogens and ligands from viruses to parasites, such as HIV-1, measles, dengue, SARS, Helicobacter pylori, E. coli, Leishmania spp., and Schistosoma egg (Sancho and Reis e Sousa, 2012).