NR5A1 and ovarian neoplasm: This analysis indicated that 36 out of 46 (78%) ovarian tumors had appreciable NR5A1 methylation (2nd, 3rd and 4th quartile of methylation levels), and 17/46 (37%) had high levels of NR5A1 methylation (3rd and 4th quartile of methylation levels; Table II).