Recent advances in molecular biology techniques have allowed the genes responsible in most hereditary corneal dystrophies to be identified, including transforming growth factor, beta-induced (TGFBI)-related corneal dystrophies (i.e., granular corneal dystrophy, lattice corneal dystrophy type I, granular corneal dystrophy type 2 (Avellino corneal dystrophy), Reis-Bücklers corneal dystrophy, and Thiel-Behnke corneal dystrophy) [3], Meesmann corneal dystrophy [4,5], macular corneal dystrophy [6], gelatinous drop-like corneal dystrophy [7], and Fuchs’ endothelial dystrophy [8]. The gene discussed is TGFBI; the disease is Reis-Bucklers corneal dystrophy.