The aim of the present study was to investigate the 1.5-year persistence of serotype-specific antibodies after conjugate pneumococcal vaccination in patients with RA and spondyloarthropathy (SpA) treated with different antiinflammatory remedies, including TNF blockers, compared with spondyloarthropathy patients treated with NSAID/analgesics. Here, TNF is linked to rheumatoid arthritis.