Thus, compared to non-asthma control subjects significant increase in level of IgE (123.1 ± 5.0 vs. 61.1 ± 4.3, p = 0.004), resistin (24.5 ± 1.6 vs. 17.3 ± 1.3, p = 0.001) and IL-4 (18.5 ± 3.6 vs. 9.2 ± 1.4, p = 0.003) pg ml-1. This evidence concerns the gene IGHE and asthma.