When compared with brain arachnoidal tissue, 82- (P<0.001), 75- (P<0.001), 83- (P<0.001), 84- (P<0.001), and 77-fold (P<0.001) increases of EGFL6 mRNA levels were observed in meningotheliomatous, angiomatous, psammomatous, transitional, and secretory meningiomas, respectively (Figure 4B). The gene discussed is EGFL6; the disease is meningioma.