qRT-PCR analysis showed up-regulation of most of integrins in tumor tissues, including ITGA2 (33.5-fold), ITGA3 (5.58-fold), ITGA6 (8.58-fold), ITGA7 (4.57-fold), ITGA10 (5.34-fold), ITGA11 (6.52-fold), ITGAV (4.87-fold), ITGB1 (13.95-fold), ITGB3 (3.34-fold), ITGB5 (5.05-fold), and ITGB8 (11.21-fold) (Figure 3C). This evidence concerns the gene ITGB5 and neoplasm.