In addition, our microarray analysis also revealed some novel p53 target genes, such as ACBD4, APOBEC3C, and FLJ14327 (Figures 9 and 10), which would not be identified by simply overexpressing ectopic p53 in cancer cell lines [20], [53], because INZ-activated p53 is acetylated [17], although further studies of these new p53 target genes are necessary to determine whether and how these genes, such as APOBEC3C (Figure 11), might act in the p53 signaling pathway. The gene discussed is TP53; the disease is cancer.