CCN2 and myocardial infarction: Although the s-CTGF levels were not statistically different at any time point during follow-up among the groups, the statistical analysis revealed significant intra-patient variation during infarct healing with the patient cohort segregating into two sub-groups; one in which s-CTGF levels increased after MI, and the other in which s-CTGF levels remained unaltered or decreased.