Th17 cells are associated with the production of inflammation mediators, and it has been observed by several groups that SLE patients have an enhanced Th17 cell response [20], [21], which is different from our results showing that there is no elevation of CD4+ CCR6+ cell percentage in PBMCs from SLE patients as compared to that from normal controls. This evidence concerns the gene CD4 and systemic lupus erythematosus.