In contrast to our findings in HACs, CysLT concentrations were not correlated with the amounts of other mediators, but LTB4 concentrations were positively correlated with the levels of some chemokines, including MCP-1 and IP-10, and cytokines, including IL-17, IL-23 and IL-10 in HAM/TSP patients (Figure 5B). Here, IL10 is linked to tropical spastic paraparesis.