A number of other relatively small intra-genic aberrations were also detected, including a focal deletion in PTEN in a basal-like tumor (Fig. 1B), an intra-genic deletion in RB1 in a different basal-like tumor (Fig. 1C), and a small RB1 amplification in yet a third basal-like tumor (Fig. 1D). This evidence concerns the gene PTEN and neoplasm.