Sathyanarayana et al. investigated promoter methylation of 12 genes in a series of 68 BCC samples and 58 non-malignant lesions (skin tags) and showed that laminin gamma 2 (LAMC2), cadherin 1 (CDH1) and RASSF1A were significantly more often methylated in BCC. The gene discussed is CDH1; the disease is skin basal cell carcinoma.