To our knowledge, studies investigating common gene polymorphisms and their correlations with increased body mass index have not thus far focused extensively on a role for DNA repair glycosylases such as Ogg1 or Neil1. Given the emerging link between these glycosylases and metabolic syndrome, a retrospective screen of specimens collected in previous studies may help shed light on potential correlations between inactivating mutations in Ogg1 and metabolic disease. This evidence concerns the gene OGG1 and Other metabolic disease.