Additionally, when tumor samples were categorized according to the presence or absence of membrane staining for TRAIL-receptors, patients with tumors exhibiting TRAIL-R1 staining on the surface of cell membranes were shown to have a better prognosis vs. patients with cytoplasmatic or no staining (5- year survival 65% vs. 44%; 10-year survival: 30% vs. 22%, p = 0.003 – Figure 4B). Here, TNFRSF10A is linked to neoplasm.