However, if patients were stratified according to the presence or absence of staining on the cell membranes, membrane staining for TRAIL-R2 in tumor samples correlated with a significantly better patient survival (5-year survival: 83% vs. 57%; 10-year survival: 38% vs. 26% p = 0.015; Figure 4D). Here, TNFRSF10B is linked to neoplasm.